Comparison of Glycine versus Sterile Water Use in Transurethral Resection of the Prostate (TURP): A Cross Sectional Study

Abstract

Introduction: All endoscopic surgery in urology needs irrigant fluid for the clear visibility and to wash out the blood and debris. Glycine 1.5% is widely accepted, but sterile water is cheaper and easily available. All types of irrigants are responsible to cause electrolyte disturbance in different degrees. In our study, we compared glycine 1.5% with sterile water as the irrigant fluid.
Methods: In this prospective, observational study where 64 patients were included with 31 patients on the sterile group and 33 patients in the Glycine group. Hemoglobin, sodium, and potassium was analyzed postoperatively after 6 hours. Weight of prostate, resection volume, volume of fluid, and resection time were calculated.
Results: There were changes in the parameters of hemoglobin and sodium but was not statically significant, whereas the change in potassium was statically significant in both groups.
Conclusions: Sterile water is safe, inexpensive, and easy available fluid for TURP compared to glycine 1.5%. Study did not show any significant difference in using both fluids, our sample size was small and so needs a similar study with large sample size to confirm the observation.