Panhypopituitarism due to Sheehan’s Syndrome in a Patient with Recurrent Hyponatremia: Case Report from Nepal

Abstract

Introduction: Panhypopituitarism, deficiency of all pituitary hormones (anterior pituitary
hormones: adrenocorticotropic hormone, thyroid-stimulating hormone, luteinizing hormone,
follicle-stimulating hormone, prolactin, growth hormone; posterior pituitary hormones:
oxytocin, vasopressin). Sheehan’s syndrome also known as postpartum hypopituitarism is one
of the causes of panhypopituitarism, which is characterized by hypopituitarism due to necrosis
of pituitary gland secondary to massive postpartum hemorrhage. In this case, a 50 years
female presented with the history of vomiting and loss of appetite since 2 years with severe
hyponatremia, and decreased pituitary hormones levels in laboratory findings with significant
obstetric history is diagnosed with Sheehan’s Syndrome.